Bioimaging data are increasingly large and complex; so too are the tools needed to interact with it. Historically, with small data and simple analyses, single-file images and one-off scripts have sufficed. Larger data, stored on the cloud, requiring greater engineering effort to access and analyse, also require new formats and interoperable metadata standards. NGFF describes an open-source, community-driven approach to developing these standards, on top of Zarr, an open-source cloud-native format for large array data of any dimensionality. OME-Zarr promises a standardised image format with broad and growing tool support, for findable, accessible, interoperable, and reusable data.